A large number of studies have shown that intestinal flora is closely related to diabetes, liver disease, cardio-cerebrovascular disease, kidney disease, AIDS, tumor and other diseases Plays a vital role in health and disease。 Intestinal flora of metabolites on the human body to produce effect by using metabonomics to detect the dynamic changes of the intestinal bacteria metabolites, clearly shows the intestinal flora in the metabolic state of the host, can be more intuitive study the relationship between intestinal flora and disease development, and for the prevention of disease and treatment, improve the health of the host provides new train of thought Through KEGG BIOML CGR HBC GMrepo and other databases combined with literature and metagomic deep sequencing data,Biotree independently constructed the intestinal microbiota metabolome database, covering 2800+ strains and 1200+ intestinal microbiota related metabolites, which can not only effectively extract metabolites The metabolites can be traced to specific strains (some of them are species). It will greatly facilitate the research on the mechanism of intestinal flora and health.
Technical advantage
Covering 2800+ species and 1200+ intestinal microbiota related metabolites, the number of metabolites and strains is huge
Not only can the metabolites of many species be traced and classified, but also the metabolites can be traced to bacterial strains. Metabolites can identify upstream and downstream relationships (if reversible) and regulate genes/enzymes.
Technical specification
Sample Requirements
Feces and intestinal contents 200 mg /sample
thick liquid 200 μL/sample
culture solution ≥200 μL/sample（推荐0.5mL/sample）
Testing platform
UHPLC-QE-MS/UHPLC-QTOF-MS
Direction of application
Dynamic changes of intestinal microbiota metabolites
Screening for differential metabolites of intestinal flora
Study on the mechanism of intestinal flora in the occurrence and development of diseases
